Velnoryx™

Questions

Frequently asked questions

The questions people ask us most, answered without the jargon.

Still unsure about something? Ask your healthcare provider or pharmacist — they know your history and can answer for your situation.

Approval code: VEL-US-12055-01 | 06/2025

Important Safety Information

What should I know about Velnoryx™?

Velnoryx™ contains epinephrine, a medication used to treat life-threatening allergic emergencies (anaphylaxis). Anaphylaxis can occur within minutes and may result from insect stings, allergy shots, certain foods, medications, exercise, or unknown triggers.

Always carry two Velnoryx™ nasal sprays with you since anaphylaxis can be unpredictable, and a second dose may be necessary if symptoms persist or return. Each Velnoryx™ contains a single dose of epinephrine and is designed for intranasal use only.

Use Velnoryx™ immediately at the first sign of an allergic reaction. If symptoms persist or worsen after the initial dose, administer a second dose using a new Velnoryx™ spray in the same nostril, waiting at least 10 minutes between doses. After using Velnoryx™, seek emergency medical attention for further care.

Before using Velnoryx™, inform your healthcare provider if:

  • You have nasal conditions that may affect its use.
  • You have any underlying medical conditions, especially heart problems, high blood pressure, thyroid disorders, Parkinson's disease, diabetes, kidney problems, or low potassium levels in your blood.
  • You are pregnant, planning to become pregnant, or breastfeeding.
  • You take other medications, such as nasal sprays, diuretics, antidepressants, or medicines for heart disease, allergies, or labor. Velnoryx™ may interact with other medications, potentially causing side effects or altering how the medicines work.

What are the potential side effects of Velnoryx™?

Velnoryx™ may cause serious side effects. If you have certain medical conditions or take specific medications, you could experience increased or prolonged side effects.

Common side effects include nasal discomfort, headache, throat irritation, chest or nasal congestion, feelings of nervousness or excitement, nosebleeds, nasal pain, sneezing, runny or dry nose, dry throat, tingling sensations (including in the nose), fatigue, dizziness, nausea, and vomiting.

If you experience side effects that are bothersome or do not resolve, inform your healthcare provider.

This is not a comprehensive list of all possible side effects. For medical advice about side effects, reach out to your healthcare provider. To report side effects, contact NeurovaRx Pharmaceuticals Operations, Inc.

Please see the full Important Safety Information and talk with your healthcare provider.

Important Safety Information

Velnoryx™ contains epinephrine, used to treat life-threatening allergic emergencies (anaphylaxis). Always carry two Velnoryx™ nasal sprays. Use Velnoryx™ immediately at the first sign of an allergic reaction, and seek emergency medical attention after use.

Full Important Safety InformationPrescribing InformationPatient InformationInstructions for Use